Alibaba Qwen · 122B total / 10B active · MoE

Best hardware to run Qwen3.5 122B-A10B locally

Qwen3.5 122B-A10B needs about 79 GB at Q4_K_M. 10 of the 17 priced rigs we track can hold it. Here's the cheapest, the best value and the fastest. Prices & stock checked 2026-10-23. Prices change daily and some retailers block our checker, so always confirm on the store page.

Our picks

Strix HaloOut of stock

Framework Desktop DIY

Ryzen AI Max+ 395, 128GB

$3,449at Framework store

Cheapest that fits. Lowest price we've seen on any tracked rig that holds Qwen3.5 122B-A10B at 4-bit (79 of 96 GB usable).

Fits~29 tok/sQ4_K_M
Check price
Strix HaloOut of stock

Framework Desktop DIY

Ryzen AI Max+ 395, 128GB

$3,449at Framework store

Best value. Lowest price per token/sec among complete systems where it fits comfortably: about $120 per tok/s at 4-bit. Same machine as the cheapest pick.

Fits~29 tok/sQ4_K_M
Check price
RTX PRO 6000Out of stock

PNY NVIDIA RTX PRO 6000 Blackwell

96GB card

$17,899at B&H Photo

Fastest. Most memory bandwidth of the rigs that fit it (1,792 GB/s), so the quickest decode: ~152 tok/s at 4-bit.

Fits~152 tok/sQ4_K_M

GPU price is card only: you still need a host PC.

Check price

Which quant to use

Use Q4_K_M on most rigs: it needs ~79 GB. Q8_0 would need ~138 GB, which doesn't fit comfortably at a usable speed on anything we track.

Every rig that fits it

MachinePrice4-bit fit & speedSuggested quant$ per tok/s
Framework Desktop DIYStrix Halo$3,449
Fits~29 tok/s
Q4_K_M$120
GMKtec EVO-X2Strix Halo$3,500
Fits~29 tok/s
Q4_K_M$121
Minisforum MS-S1 MaxStrix Halo$3,919
Fits~29 tok/s
Q4_K_M$136
Beelink GTR9 ProStrix Halo$4,349
Fits~29 tok/s
Q4_K_M$151
Lenovo ThinkStation PGXDGX Spark / GB10$5,859
Fits~31 tok/s
Q4_K_M$189
ASUS Ascent GX10DGX Spark / GB10$5,999
Fits~31 tok/s
Q4_K_M$193
NVIDIA DGX SparkDGX Spark / GB10$6,950
Fits~31 tok/s
Q4_K_M$224
HP ZGX Nano G1nDGX Spark / GB10$7,699
Fits~31 tok/s
Q4_K_M$248
Gigabyte AI TOP ATOMDGX Spark / GB10$8,499
Fits~31 tok/s
Q4_K_M$274
PNY NVIDIA RTX PRO 6000 BlackwellRTX PRO 6000 (card only, needs a host PC)$17,899
Fits~152 tok/s
Q4_K_M$118

Sorted by lowest price. Speeds are estimated single-user decode at ~8K context. Full fit table, including rigs that don't fit: Qwen3.5 122B-A10B memory requirements. How we estimate

FAQ

How much memory does Qwen3.5 122B-A10B need?

About 79 GB at Q4_K_M and 138 GB at Q8_0, including runtime overhead and ~8K tokens of context for one user. Longer context needs more.

What's the cheapest hardware to run Qwen3.5 122B-A10B locally?

Of the rigs we track, the Framework Desktop DIY at $3,449, estimated ~29 tok/s at 4-bit. Prices checked 2026-10-23.

Which quant should I use for Qwen3.5 122B-A10B?

Q4_K_M is the default: about 79 GB. Q8_0 needs about 138 GB; use it only if you have the room and still get usable speed.

How fast does Qwen3.5 122B-A10B run?

It has 10B active parameters per token, so speed is set by memory bandwidth: from ~29 tok/s on the slowest rig that fits to ~152 tok/s on the PNY NVIDIA RTX PRO 6000 Blackwell. Estimates, not benchmarks.

Related guides

Restock & price-drop alerts

One short email a week: what got cheaper, what's back in stock, and which new open models your machine can run. Unsubscribe anytime.